Lois Pewterschmidt is the wife of Peter Griffin. With out her, the whole family would fall apart, she provides a voice of reason and sense.
Lois teaches the piano during the afternoon and spends the rest of her time doing housework and looking after the family. She has her hands full looking after their baby Stewie who has grown a dangerous dislike to her.
When she needs someone to turn to she chats with Brian, the family dog. As perhaps the only two members of the family with an ounce of sanity they find they have a lot in common.
Lois comes from a wealthy background, and met Peter whilst spending the summer at her aunts summer house in Newport where Peter was working as a towel boy.
Best known for her wildly popular character "Ms. Swan" on MADtv, Alex Borstein starred opposite George Clooney in the Academy Award®-nominated 2005 feature film Good Night, and Good Luck. In addition to providing the voice of Lois on Family Guy, she also serves as a writer/producer on the show.
Borstein is no stranger to the film world. In addition to Good Night, and Good Luck, she starred in the Wayans brothers' Little Man and in Scott Frank's The Lookout. She also appeared opposite Halle Barry in Catwoman, as well as various other features, including Kicking and Screaming, The Lizzie McGuire Movie, Coyote Ugly, Showtime, Bad Boys and Bad Santa. She was more recently seen in Killers alongside Ashton Kutcher and Katherine Heigl and Dinner for Schmucks with Steve Carell and Paul Rudd.
Originally from Chicago, Borstein moved to Los Angeles at a young age. She graduated from San Francisco State University with a degree in Rhetoric. She started performing improvisation while in San Francisco and later joined the ACME Comedy Theatre in Los Angeles. In November 2006, her critically heralded one-woman stand-up show, Drop Dead Gorgeous in a Down to Earth Bombshell Sort of Way, was released on DVD.