Nurse Jackie is a dark comedy that is at turns wicked, heartbreaking and funny. Edie Falco - who won the 2010 Emmy Award winner for Best Supporting Actress in Nurse Jackie - stars as the title character Jackie Peyton, a strong-willed and brilliant - but very flawed - emergency room nurse working in the complicated and frenzied environment of a New York City hospital.

A lapsed Catholic with a weakness for painkillers to get her through the days, Jackie keeps the hospital balanced with her unique bedside manner and own brand of medical justice. Every day is a high-wire act of juggling patients, doctors and fellow nurses along with her indiscretions.

Jackie's relentless dedication to her profession and her family come into conflict with the complicated decisions she’s faced with on an hourly basis, leaving her in many moral and ethical quandaries that she somehow must find a way to figure out.

The series also stars Eve Best, Peter Facinelli, Merritt Wever, Haaz Sleiman and Paul Schulze, and features Anna Deavere Smith and Dominic Fumusa.